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参考文献: UCHL1

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Nanok C, Jearanaikoon P, Proungvitaya S, Limpaiboon T. Aberrant methylation of HTATIP2 and UCHL1 as a predictive biomarker for cholangiocarcinoma. Mol Med Rep. 2018 Mar;17(3):4145-4153. doi
Jamin A, Berthelot L, Couderc A, Chemouny JM, Boedec E, Dehoux L, Abbad L, Dossier C, Daugas E, Monteiro RC, Deschnes G. Autoantibodies against podocytic UCHL1 are associated with idiopathic nephrotic syndrome relapses and induce proteinuria in mice. J Autoimmun. 2018 Jan 4. pii
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Wang Y, Wang L, Gao H, Gao Y, Yang C, Ji H, Dong W. UCHL1 expression and localization on testicular development and spermatogenesis of Chinese giant salamanders. Oncotarget. 2017 Sep 15;8(49):86043-86055. doi: 10.18632/oncotarget.20910. eCollection 2017 Oct 17. PubMed
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Song IK, Kim HJ, Magesh V, Lee KJ. Ubiquitin C-terminal hydrolase-L1 plays a key role in angiogenesis by regulating hydrogen peroxide generated by NADPH oxidase 4. Biochem Biophys Res Commun. 2018 Jan 1;495(1):1567-1572. doi: 10.1016/j.bbrc.2017.11.051. Epub 2017 Nov 8. PubMed
Ilic A, Lu S, Bhatia V, Begum F, Klonisch T, Agarwal P, Xu W, Davie JR. Ubiquitin C-terminal hydrolase isozyme L1 is associated with shelterin complex at interstitial telomeric sites. Epigenetics Chromatin. 2017 Nov 10;10(1):54. doi: 10.1186/s13072-017-0160-2. PubMed
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Fang Y, Shen X. Ubiquitin carboxyl-terminal hydrolases
Agoston DV, Shutes-David A, Peskind ER. Biofluid biomarkers of traumatic brain injury. Brain Inj. 2017;31(9):1195-1203. doi: 10.1080/02699052.2017.1357836. PubMed
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Matuszczak E, Sankiewicz A, Debek W, Gorodkiewicz E, Milewski R, Hermanowicz A. Immunoproteasome in the blood plasma of children with acute appendicitis, and its correlation with proteasome and UCHL1 measured by SPR imaging biosensors. Clin Exp Immunol. 2018 Jan;191(1):125-132. doi
Hanpude P, Bhattacharya S, Kumar Singh A, Kanti Maiti T. Ubiquitin recognition of BAP1
Ott CA, Baljinnyam B, Zakharov AV, Jadhav A, Simeonov A, Zhuang Z. Cell Lysate-Based AlphaLISA Deubiquitinase Assay Platform for Identification of Small Molecule Inhibitors. ACS Chem Biol. 2017 Sep 15;12(9):2399-2407. doi: 10.1021/acschembio.7b00543. Epub 2017 Aug 24. PubMed
Gao H, Hartnett S, Li Y. Ubiquitin C-Terminal Hydrolase L1 regulates myoblast proliferation and differentiation. Biochem Biophys Res Commun. 2017 Oct 7;492(1):96-102. doi
Liu H, Zhou T, Wang B, Li L, Ye D, Yu S. Identification and functional analysis of a potential key lncRNA involved in fat loss of cancer cachexia. J Cell Biochem. 2018 Feb;119(2):1679-1688. doi
Wang J, Liu Y, Chen T. Identification of key genes and pathways in Parkinson's disease through integrated analysis. Mol Med Rep. 2017 Oct;16(4):3769-3776. doi
Nakashima R, Goto Y, Koyasu S, Kobayashi M, Morinibu A, Yoshimura M, Hiraoka M, Hammond EM, Harada H. UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization. Sci Rep. 2017 Jul 31;7(1):6879. doi
Zhang D, Han S, Wang S, Luo Y, Zhao L, Li J. cPKCγ-mediated down-regulation of UCHL1 alleviates ischaemic neuronal injuries by decreasing autophagy via ERK-mTOR pathway. J Cell Mol Med. 2017 Dec;21(12):3641-3657. doi: 10.1111/jcmm.13275. Epub 2017 Jul 20. PubMed
Park S, Zhang X, Li C, Yin C, Li J, Fallon JT, Huang W, Xu D. Single-cell RNA sequencing reveals an altered gene expression pattern as a result of CRISPR/cas9-mediated deletion of Gene 33/Mig6 and chronic exposure to hexavalent chromium in human lung epithelial cells. Toxicol Appl Pharmacol. 2017 Sep 1;330:30-39. doi
Cheng JC, Tseng CP, Liao MH, Peng CY, Yu JS, Chuang PH, Huang JT, Chen JJW. Activation of hepatic stellate cells by the ubiquitin C-terminal hydrolase 1 protein secreted from hepatitis C virus-infected hepatocytes. Sci Rep. 2017 Jun 30;7(1):4448. doi
Matuszczak E, Tylicka M, Dębek W, Tokarzewicz A, Gorodkiewicz E, Hermanowicz A. Concentration of UHCL1 in the Serum of Children with Acute Appendicitis, Before and After Surgery, and Its Correlation with CRP and Prealbumin. J Invest Surg. 2017 Feb 27:1-6. doi
Hosseinibarkooie S, Schneider S, Wirth B. Advances in understanding the role of disease-associated proteins in spinal muscular atrophy. Expert Rev Proteomics. 2017 Jul;14(7):581-592. doi
Stephen JK, Chen KM, Merritt J, Chitale D, Divine G, Worsham MJ. Methylation markers differentiate thyroid cancer from benign nodules. J Endocrinol Invest. 2018 Feb;41(2):163-170. doi
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Guo YY, Lu Y, Zheng Y, Chen XR, Dong JL, Yuan RR, Huang SH, Yu H, Wang Y, Chen ZY, Su B. Ubiquitin C-Terminal Hydrolase L1 (UCH-L1) Promotes Hippocampus-Dependent Memory via Its Deubiquitinating Effect on TrkB. J Neurosci. 2017 Jun 21;37(25):5978-5995. doi
Sanchez-Diaz PC, Chang JC, Moses ES, Dao T, Chen Y, Hung JY. Ubiquitin carboxyl-terminal esterase L1 (UCHL1) is associated with stem-like cancer cell functions in pediatric high-grade glioma. PLoS One. 2017 May 4;12(5):e0176879. doi
Zhang Y, Huang X, Zhao XY, Hu YJ, Sun HY, Kong WJ. Role of the Ubiquitin C-Terminal Hydrolase L1-Modulated Ubiquitin Proteasome System in Auditory Cortex Senescence. ORL J Otorhinolaryngol Relat Spec. 2017;79(3):153-163. doi: 10.1159/000468944. Epub 2017 Apr 14. PubMed
Reynolds JP, Jimenez-Mateos EM, Cao L, Bian F, Alves M, Miller-Delaney SF, Zhou A, Henshall DC. Proteomic Analysis After Status Epilepticus Identifies UCHL1 as Protective Against Hippocampal Injury. Neurochem Res. 2017 Jul;42(7):2033-2054. doi
Seo EY, Jin SP, Sohn KC, Park CH, Lee DH, Chung JH. UCHL1 Regulates Melanogenesis throughControlling MITF Stability in Human Melanocytes. J Invest Dermatol. 2017 Aug;137(8):1757-1765. doi
Van Gerven L, Alpizar YA, Steelant B, Callebaut I, Kortekaas Krohn I, Wouters M, Vermeulen F, Boeckxstaens G, Talavera K, Hellings PW. Enhanced chemosensory sensitivity in patients with idiopathic rhinitis and its reversal by nasal capsaicin treatment. J Allergy Clin Immunol. 2017 Aug;140(2):437-446.e2. doi: 10.1016/j.jaci.2017.03.014. Epub 2017 Apr 4. PubMed
Singh D, Paduch DA, Schlegel PN, Orwig KE, Mielnik A, Bolyakov A, Wright WW. The production of glial cell line-derived neurotrophic factor by human sertoli cells is substantially reduced in sertoli cell-only testes. Hum Reprod. 2017 May 1;32(5):1108-1117. doi
Rydning SL, Backe PH, Sousa MML, Iqbal Z, ye AM, Sheng Y, Yang M, Lin X, Slupphaug G, Nordenmark TH, Vigeland MD, Bjrs M, Tallaksen CM, Selmer KK. Novel UCHL1 mutations reveal new insights into ubiquitin processing. Hum Mol Genet. 2017 Mar 15;26(6):1217-1218. doi
Nencini S, Ringuet M, Kim DH, Chen YJ, Greenhill C, Ivanusic JJ. Mechanisms of nerve growth factor signaling in bone nociceptors and in an animal model of inflammatory bone pain. Mol Pain. 2017 Jan;13:1744806917697011. doi: 10.1177/1744806917697011. PubMed
Kumar R, Jangir DK, Verma G, Shekhar S, Hanpude P, Kumar S, Kumari R, Singh N, Sarovar Bhavesh N, Ranjan Jana N, Kanti Maiti T. S-nitrosylation of UCHL1 induces its structural instability and promotes α-synuclein aggregation. Sci Rep. 2017 Mar 16;7:44558. doi
Shi Z, Chen T, Yao Q, Zheng L, Zhang Z, Wang J, Hu Z, Cui H, Han Y, Han X, Zhang K, Hong W. The circular RNA ciRS-7 promotes APP and BACE1 degradation in an NF-κB-dependent manner. FEBS J. 2017 Apr;284(7):1096-1109. doi: 10.1111/febs.14045. Epub 2017 Mar 13. PubMed
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Matuszczak E, Tylicka M, Dębek W, Sankiewicz A, Gorodkiewicz E, Hermanowicz A. Overexpression of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) in serum of children after thermal injury. Adv Med Sci. 2017 Mar;62(1):83-86. doi: 10.1016/j.advms.2016.07.004. Epub 2017 Feb 11. PubMed
Hu Q, Guo F, Zhao F, Fu Z. Effects of titanium dioxide nanoparticles exposure on parkinsonism in zebrafish larvae and PC12. Chemosphere. 2017 Apr;173:373-379. doi
Liu L, Urch B, Szyszkowicz M, Speck M, Leingartner K, Shutt R, Pelletier G, Gold DR, Scott JA, Brook JR, Thorne PS, Silverman FS. Influence of exposure to coarse, fine and ultrafine urban particulate matter and their biological constituents on neural biomarkers in a randomized controlled crossover study. Environ Int. 2017 Apr;101:89-95. doi
Liu L, Yu J, Li L, Zhang B, Liu L, Wu CH, Jong A, Mao DA, Huang SH. Alpha7 nicotinic acetylcholine receptor is required for amyloid pathology in brain endothelial cells induced by Glycoprotein 120, methamphetamine and nicotine. Sci Rep. 2017 Jan 11;7:40467. doi
Noguchi A, Tominaga M, Takahashi N, Matsuda H, Kamata Y, Umehara Y, Ko KC, Suga Y, Ogawa H, Takamori K. Differences in therapeutic effects of topically applied corticosteroid and tacrolimus on atopic dermatitis-like symptoms in NC/Nga mice. J Dermatol Sci. 2017 Apr;86(1):54-62. doi: 10.1016/j.jdermsci.2016.12.015. Epub 2016 Dec 24. PubMed
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Rydning SL, Backe PH, Sousa MML, Iqbal Z, ye AM, Sheng Y, Yang M, Lin X, Slupphaug G, Nordenmark TH, Vigeland MD, Bjrs M, Tallaksen CM, Selmer KK. Novel UCHL1 mutations reveal new insights into ubiquitin processing. Hum Mol Genet. 2017 Mar 15;26(6):1031-1040. doi
Zhang H, Jackson SE. Characterization of the Folding of a 5(2)-Knotted Protein Using Engineered Single-Tryptophan Variants. Biophys J. 2016 Dec 20;111(12):2587-2599. doi
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Rani A, Roy S, Singh M, Devi U, Yadav RK, Gautam S, Rawat JK, Ansari MN, Saeedan AS, Prakash A, Kaithwas G. α-Chymotrypsin regulates free fatty acids and UCHL-1 to ameliorate N-methyl nitrosourea induced mammary gland carcinoma in albino wistar rats. Inflammopharmacology. 2016 Oct;24(5):277-286. Epub 2016 Sep 26. PubMed
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Cheng W, Chen YL, Wu L, Miao B, Yin Q, Wang JF, Fu ZJ. Inhibition of spinal UCHL1 attenuates pain facilitation in a cancer-induced bone pain model by inhibiting ubiquitin and glial activation. Am J Transl Res. 2016 Jul 15;8(7):3041-8. eCollection 2016. PubMed
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Rhine T, Babcock L, Zhang N, Leach J, Wade SL. Are UCH-L1 and GFAP promising biomarkers for children with mild traumatic brain injury? Brain Inj. 2016;30(10):1231-8. doi
Nisenblat V, Prentice L, Bossuyt PM, Farquhar C, Hull ML, Johnson N. Combination of the non-invasive tests for the diagnosis of endometriosis. Cochrane Database Syst Rev. 2016 Jul 13;7:CD012281. doi: 10.1002/14651858.CD012281. Review. PubMed
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Schrempf W, Katona I, Dogan I, Felbert VV, Wienecke M, Heller J, Maier A, Hermann A, Linse K, Brandt MD, Reichmann H, Schulz JB, Schiefer J, Oertel WH, Storch A, Weis J, Reetz K. Reduced intraepidermal nerve fiber density in patients with REM sleep behavior disorder. Parkinsonism Relat Disord. 2016 Aug;29:10-6. doi
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Yu XY, Zhang L, Yang XY, Li XT, Du GH. Salvianolic acid A improves intestinal motility in diabetic rats through antioxidant capacity and upregulation of nNOS. J Dig Dis. 2016 Jul;17(7):441-7. doi
Shruthi K, Reddy SS, Reddy PY, Shivalingam P, Harishankar N, Reddy GB. Amelioration of neuronal cell death in a spontaneous obese rat model by dietary restriction through modulation of ubiquitin proteasome system. J Nutr Biochem. 2016 Jul;33:73-81. doi
Gen B, Jara JH, Schultz MC, Manuel M, Stanford MJ, Gautam M, Klessner JL, Sekerkova G, Heller DB, Cox GA, Heckman CJ, DiDonato CJ, zdinler PH. Absence of UCHL 1 function leads to selective motor neuropathy. Ann Clin Transl Neurol. 2016 Mar 7;3(5):331-45. doi
Van Acker N, Rag M, Sluydts E, Knaapen MW, De Bie M, Timmers M, Fransen E, Duymelinck C, De Schepper S, Anand P, Meert T, Plaghki L, Cras P. Automated PGP9.5 immunofluorescence staining
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Bracalente C, Ibaez IL, Berenstein A, Notcovich C, Cerda MB, Klamt F, Chernomoretz A, Durn H. Reprogramming human A375 amelanotic melanoma cells by catalase overexpression
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Lou SC, Wetzel S, Zhang H, Crone EW, Lee YT, Jackson SE, Hsu ST. The Knotted Protein UCH-L1 Exhibits Partially Unfolded Forms under Native Conditions that Share Common Structural Features with Its Kinetic Folding Intermediates. J Mol Biol. 2016 Jun 5;428(11):2507-20. doi
Papa L, Brophy GM, Welch RD, Lewis LM, Braga CF, Tan CN, Ameli NJ, Lopez MA, Haeussler CA, Mendez Giordano DI, Silvestri S, Giordano P, Weber KD, Hill-Pryor C, Hack DC. Time Course and Diagnostic Accuracy of Glial and Neuronal Blood Biomarkers GFAP and UCH-L1 in a Large Cohort of Trauma Patients With and Without Mild Traumatic Brain Injury. JAMA Neurol. 2016 May 1;73(5):551-60. doi: 10.1001/jamaneurol.2016.0039. PubMed
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Zhang H, Li Y, de Carvalho-Barbosa M, Kavelaars A, Heijnen CJ, Albrecht PJ, Dougherty PM. Dorsal Root Ganglion Infiltration by Macrophages Contributes toPaclitaxel Chemotherapy-Induced Peripheral Neuropathy. J Pain. 2016 Jul;17(7):775-86. doi
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