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参考文献: Axl

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Wang ZY, Wang PG, An J. The Multifaceted Roles of TAM Receptors during Viral Infection. Virol Sin. 2020 Jul 27. doi
Chen YQ, Zhou HM, Chen FF, Liu YP, Han L, Song M, Wang ZH, Zhang W, Shang YY, Zhong M. Testosterone ameliorates vascular aging via the Gas6/Axl signaling pathway. Aging (Albany NY). 2020 Jul 27;12. doi
Zou Z, Sun J, Kang Z, Wang Y, Zhao H, Zhu K, Wang J. Tyrosine Kinase Receptors Axl and MerTK Mediate the Beneficial Effect of Electroacupuncture in a Cuprizone-Induced Demyelinating Model. Evid Based Complement Alternat Med. 2020 Jul 4;2020:3205176. doi
Wang F, Chen R, Jiang Q, Wu H, Gong M, Liu W, Yu X, Zhang W, Han R, Liu A, Chen Y, Han D. Roles of Sialic Acid, AXL, and MER Receptor Tyrosine Kinases in Mumps Virus Infection of Mouse Sertoli and Leydig Cells. Front Microbiol. 2020 Jun 29;11:1292. doi
Park JH, Yang H, Kwon H, Jeon S. Risk factors for onset or progression of posterior vitreous detachment at the vitreomacular interface after cataract surgery. Ophthalmol Retina. 2020 Jul 17. pii
Abu-Thuraia A, Goyette MA, Boulais J, Delliaux C, Apcher C, Schott C, Chidiac R, Bagci H, Thibault MP, Davidson D, Ferron M, Veillette A, Daly RJ, Gingras AC, Gratton JP, Ct JF. AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network. Nat Commun. 2020 Jul 17;11(1):3586. doi
Steiner CA, Rodansky ES, Johnson LA, Berinstein JA, Cushing KC, Huang S, Spence JR, Higgins PDR. AXL Is a Potential Target for the Treatment of Intestinal Fibrosis. Inflamm Bowel Dis. 2020 Jul 17. pii
Li Q, Wang X, Jiang N, Xie X, Liu N, Liu J, Shen J, Peng T. Exosome-transmitted linc00852 associated with receptor tyrosine kinase AXL dysregulates the proliferation and invasion of osteosarcoma. Cancer Med. 2020 Jul 16. doi
Trojan J. Cabozantinib for the Treatment of Advanced Hepatocellular Carcinoma
Al Kafri N, Hafizi S. Galectin-3 Stimulates Tyro3 Receptor Tyrosine Kinase and Erk Signalling, Cell Survival and Migration in Human Cancer Cells. Biomolecules. 2020 Jul 11;10(7). pii
Tanaka M, Siemann DW. Gas6/Axl Signaling Pathway in the Tumor Immune Microenvironment. Cancers (Basel). 2020 Jul 9;12(7). pii
Jiang C, Cheng Z, Jiang T, Xu Y, Wang B. MicroRNA-34a inhibits cell invasion and epithelial-mesenchymal transition via targeting AXL/PI3K/AKT/Snail signaling in nasopharyngeal carcinoma. Genes Genomics. 2020 Aug;42(8):971-978. doi: 10.1007/s13258-020-00963-3. Epub 2020 Jul 9. PubMed
Bouhaddou M, Memon D, Meyer B, White KM, Rezelj VV, Correa Marrero M, Polacco BJ, Melnyk JE, Ulferts S, Kaake RM, Batra J, Richards AL, Stevenson E, Gordon DE, Rojc A, Obernier K, Fabius JM, Soucheray M, Miorin L, Moreno E, Koh C, Tran QD, Hardy A, Robinot R, Vallet T, Nilsson-Payant BE, Hernandez-Armenta C, Dunham A, Weigang S, Knerr J, Modak M, Quintero D, Zhou Y, Dugourd A, Valdeolivas A, Patil T, Li Q, Httenhain R, Cakir M, Muralidharan M, Kim M, Jang G, Tutuncuoglu B, Hiatt J, Guo JZ, Xu J, Bouhaddou S, Mathy CJP, Gaulton A, Manners EJ, Flix E, Shi Y, Goff M, Lim JK, McBride T, O'Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, De Wit E, Leach AR, Kortemme T, Shoichet B, Ott M, Saez-Rodriguez J, tenOever BR, Mullins RD, Fischer ER, Kochs G, Grosse R, Garca-Sastre A, Vignuzzi M, Johnson JR, Shokat KM, Swaney DL, Beltrao P, Krogan NJ. The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020 Aug 6;182(3):685-712.e19. doi
Apolo AB, Nadal R, Tomita Y, Davarpanah NN, Cordes LM, Steinberg SM, Cao L, Parnes HL, Costello R, Merino MJ, Folio LR, Lindenberg L, Raffeld M, Lin J, Lee MJ, Lee S, Alarcon SV, Yuno A, Dawson NA, Allette K, Roy A, De Silva D, Lee MM, Sissung TM, Figg WD, Agarwal PK, Wright JJ, Ning YM, Gulley JL, Dahut WL, Bottaro DP, Trepel JB. Cabozantinib in patients with platinum-refractory metastatic urothelial carcinoma
Tu R, Yu J, Savini G, Ye J, Ning R, Xiong J, Chen S, Huang J. Agreement Between Two Optical Biometers Based on Large Coherence Length SS-OCT and Scheimpflug Imaging/Partial Coherence Interferometry. J Refract Surg. 2020 Jul 1;36(7):459-465. doi
Neirinckx V, Hau AC, Schuster A, Fritah S, Tiemann K, Klein E, Nazarov PV, Matagne A, Szpakowska M, Meyrath M, Chevign A, Schmidt MHH, Niclou SP. The soluble form of pan-RTK inhibitor and tumor suppressor LRIG1 mediates downregulation of AXL through direct protein-protein interaction in glioblastoma. Neurooncol Adv. 2019 Sep 6;1(1):vdz024. doi
Bruce A, Mojarrad NG, Santorelli G. Association of anthropometric measures across the life-course with refractive error and ocular biometry at age 15 years. BMC Ophthalmol. 2020 Jul 8;20(1):269. doi
Wang ZY, Zhen ZD, Fan DY, Qin CF, Han DS, Zhou HN, Wang PG, An J. Axl deficiency promotes the neuroinvasion of Japanese encephalitis virus by enhancing IL-1α production from pyroptotic macrophages. J Virol. 2020 Jul 1. pii: JVI.00602-20. doi
He L, Lei Y, Hou J, Wu J, Lv G. Implications of the Receptor Tyrosine Kinase Axl in Gastric Cancer Progression. Onco Targets Ther. 2020 Jun 22;13:5901-5911. doi
Lavelle TJ, Alver TN, Heintz KM, Wernhoff P, Nygaard V, Nakken S, y GF, Be SL, Urbanucci A, Hovig E. Dysregulation of MITF Leads to Transformation in MC1R-Defective Melanocytes. Cancers (Basel). 2020 Jun 28;12(7). pii
Antony J, Zanini E, Birtley JR, Gabra H, Recchi C. Emerging roles for the GPI-anchored tumor suppressor OPCML in cancers. Cancer Gene Ther. 2020 Jun 29. doi
Li J, Shi C, Zhou R, Han Y, Xu S, Ma H, Zhang Z. The crosstalk between AXL and YAP promotes tumor progression through STAT3 activation in head and neck squamous cell carcinoma. Cancer Sci. 2020 Jun 26. doi
Wang MS, Xu HC, Gong Y, Qu RY, Zhuo LS, Huang W. Efficient Arylation of 2,7-Naphthyridin-1(2H)-one with Diaryliodonium Salts and Discovery of a New Selective MET/AXL Kinase Inhibitor. ACS Comb Sci. 2020 Jul 10. doi: 10.1021/acscombsci.0c00074. [Epub ahead of print] PubMed
Stewart CA, Gay CM, Ramkumar K, Cargill KR, Cardnell RJ, Nilsson MB, Heeke S, Park EM, Kundu ST, Diao L, Wang Q, Shen L, Xi Y, Maria Della Corte C, Fan Y, Kundu K, Pickering CR, Johnson FM, Zhang J, Kadara H, Minna JD, Gibbons DL, Wang J, Heymach JV, Byers LA. SARS-CoV-2 infection induces EMT-like molecular changes, including ZEB1-mediated repression of the viral receptor ACE2, in lung cancer models. bioRxiv. 2020 May 29. pii
Bellan M, Quaglia M, Nerviani A, Mauro D, Lewis M, Goegan F, Gibbin A, Pagani S, Salmi L, Molinari L, Castello LM, Avanzi GC, Cantaluppi V, Pirisi M, Sainaghi PP, Pitzalis C. Increased plasma levels of Gas6 and its soluble tyrosine kinase receptors Mer and Axl are associated with immunological activity and severity of lupus nephritis. Clin Exp Rheumatol. 2020 Jun 4. [Epub ahead of print] PubMed
Zagrska A, Travs PG, Jimnez-Garca L, Strickland JD, Oh J, Tapia FJ, Mayoral R, Burrola P, Copple BL, Lemke G. Differential regulation of hepatic physiology and injury by the TAM receptors Axl and Mer. Life Sci Alliance. 2020 Jun 22;3(8). pii
Zhang X, Yang L, Szeto P, Abali GK, Zhang Y, Kulkarni A, Amarasinghe K, Li J, Vergara IA, Molania R, Papenfuss AT, McLean C, Shackleton M, Harvey KF. The Hippo pathway oncoprotein YAP promotes melanoma cell invasion and spontaneous metastasis. Oncogene. 2020 Jul;39(30):5267-5281. doi
Grzywa TM, Klicka K, Paskal W, Dudkiewicz J, Wejman J, Pyzlak M, Włodarski PK. miR-410-3p is induced by vemurafenib via ER stress and contributes to resistance to BRAF inhibitor in melanoma. PLoS One. 2020 Jun 17;15(6):e0234707. doi
Chew S, Mackey MC, Jabbour E. Gilteritinib in the treatment of relapsed and refractory acute myeloid leukemia with a FLT3 mutation. Ther Adv Hematol. 2020 Jun 3;11:2040620720930614. doi
Mao S, Wu Y, Wang R, Guo Y, Bi D, Ma W, Zhang W, Zhang J, Yan Y, Yao X. Overexpression of GAS6 Promotes Cell Proliferation and Invasion in Bladder Cancer by Activation of the PI3K/AKT Pathway. Onco Targets Ther. 2020 May 27;13:4813-4824. doi
Wang Q, Chen Z, Chen D, Ye XY. An LC-MS/MS Bioanalytical Assay for the Determination of Gilteritinib in Rat Plasma and Application to a Drug-Drug Interaction Study. Drug Des Devel Ther. 2020 May 26;14:2061-2067. doi: 10.2147/DDDT.S243760. eCollection 2020. PubMed
Li L, Liu D, Liu A, Li J, Wang H, Zhou J. Genomic Survey of Tyrosine Kinases Repertoire in Electrophorus electricus With an Emphasis on Evolutionary Conservation and Diversification. Evol Bioinform Online. 2020 May 25;16:1176934320922519. doi
Ngwa W, Kumar R, Thompson D, Lyerly W, Moore R, Reid TE, Lowe H, Toyang N. Potential of Flavonoid-Inspired Phytomedicines against COVID-19. Molecules. 2020 Jun 11;25(11). pii
Schffski P, Blay JY, Ray-Coquard I. Cabozantinib as an emerging treatment for sarcoma. Curr Opin Oncol. 2020 Jul;32(4):321-331. doi: 10.1097/CCO.0000000000000644. PubMed
Ryu YS, Shin S, An HG, Kwon TU, Baek HS, Kwon YJ, Chun YJ. Synergistic Induction of Apoptosis by the Combination of an Axl Inhibitor and Auranofin in Human Breast Cancer Cells. Biomol Ther (Seoul). 2020 Jun 15. doi: 10.4062/biomolther.2020.051. [Epub ahead of print] PubMed
Savini G, Di Maita M, Hoffer KJ, Nser K, Schiano-Lomoriello D, Vagge A, Di Cello L, Traverso CE. Comparison of 13 formulas for IOL power calculation with measurements from partial coherence interferometry. Br J Ophthalmol. 2020 Jun 10. pii
Yang YM, Jang Y, Lee SH, Kang B, Lim SM. AXL/MET dual inhibitor, CB469, has activity in non-small cell lung cancer with acquired resistance to EGFR TKI with AXL or MET activation. Lung Cancer. 2020 Aug;146:70-77. doi: 10.1016/j.lungcan.2020.05.031. Epub 2020 May 29. PubMed
Sun Y, Bailey CP, Sadighi Z, Zaky W, Chandra J. Pediatric high-grade glioma
Lechertier T, Reynolds LE, Kim H, Pedrosa AR, Gmez-Escudero J, Muoz-Flix JM, Batista S, Dukinfield M, Demircioglu F, Wong PP, Matchett KP, Henderson NC, D'Amico G, Parsons M, Harwood C, Meier P, Hodivala-Dilke KM. Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth. Nat Commun. 2020 Jun 4;11(1):2810. doi: 10.1038/s41467-020-16618-6. PubMed
Wang SJ, Li R, Ng TSC, Luthria G, Oudin MJ, Prytyskach M, Kohler RH, Weissleder R, Lauffenburger DA, Miller MA. Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy. Sci Adv. 2020 May 22;6(21):eaaz8521. doi
Kelley RK, W Oliver J, Hazra S, Benzaghou F, Yau T, Cheng AL, Rimassa L. Cabozantinib in combination with atezolizumab versus sorafenib in treatment-naive advanced hepatocellular carcinoma
Cabrera-Mendoza B, Martnez-Magaa JJ, Genis-Mendoza AD, Monroy-Jaramillo N, Walss-Bass C, Fries GR, Garca-Dolores F, Lpez-Armenta M, Flores G, Vzquez-Roque RA, Nicolini H. Brain Gene Expression-DNA Methylation Correlation in Suicide Completers
Peterfi L, Bjercke T, Yusenko MV, Kovacs G, Banyai D. Cytoplasmic Expression of AXL Is Associated With High Risk of Postoperative Relapse of Conventional Renal Cell Carcinoma. Anticancer Res. 2020 Jun;40(6):3485-3489. doi: 10.21873/anticanres.14335. PubMed
Esposito CL, Nuzzo S, Ibba ML, Ricci-Vitiani L, Pallini R, Condorelli G, Catuogno S, de Franciscis V. Combined Targeting of Glioblastoma Stem-Like Cells by Neutralizing RNA-Bio-Drugs for STAT3. Cancers (Basel). 2020 May 31;12(6). pii: E1434. doi
Shen L, Lei S, Zhang B, Li S, Huang L, Czachor A, Breitzig M, Gao Y, Huang M, Mo X, Zheng Q, Sun H, Wang F. Skipping of exon 10 in Axl pre-mRNA regulated by PTBP1 mediates invasion and metastasis process of liver cancer cells. Theranostics. 2020 Apr 27;10(13):5719-5735. doi
Martinez-Garcia M, Fernndez-Jimnez N, Santos JL, Pradillo M. Duplication and divergence
Zhu X, Meng J, He W, Rong X, Lu Y. Comparison of the rotational stability between plate-haptic toric and C-loop haptic toric intraocular lenses in myopic eyes. J Cataract Refract Surg. 2020 May 28. doi
Salouti R, Kamalipour A, Masihpour N, Zamani M, Ghoreyshi M, Salouti K, Nowroozzadeh MH. Effect of photorefractive keratectomy on agreement of anterior segment variables obtained by a swept-source biometer vs a scheimpflug-based tomographer. J Cataract Refract Surg. 2020 May 28. doi: 10.1097/j.jcrs.0000000000000252. [Epub ahead of print] PubMed
Klinge U, Dievernich A, Tolba R, Klosterhalfen B, Davies L. CD68+ macrophages as crucial components of the foreign body reaction demonstrate an unconventional pattern of functional markers quantified by analysis with double fluorescence staining. J Biomed Mater Res B Appl Biomater. 2020 May 30. doi: 10.1002/jbm.b.34639. [Epub ahead of print] PubMed
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Saito T, Itoh M, Tohda S. Metformin suppresses the growth of leukemia cells partly through downregulation of AXL receptor tyrosine kinase. Leuk Res. 2020 Jul;94:106383. doi
Ridwan AY, Wu J, Harada E, D Alessandro-Gabazza CN, Toda M, Yasuma T, Gabazza EC, Choi JH, Hirai H, Kawagishi H. Axl and immune checkpoints inhibitors from fruiting bodies of Pleurocybella porrigens. J Antibiot (Tokyo). 2020 May 27. doi: 10.1038/s41429-020-0323-4. [Epub ahead of print] PubMed
Kwon J, Helfman DM, Kim MY. AKT drives sustained motility following MEK inhibition via promoting SNAIL and AXL in MDA-MB-231 LM2. Biochem Biophys Res Commun. 2020 Jul 12;528(1):92-98. doi
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Park SK, Byun WS, Lee S, Han YT, Jeong YS, Jang K, Chung SJ, Lee J, Suh YG, Lee SK. A novel small molecule STAT3 inhibitor SLSI-1216 suppresses proliferation and tumor growth of triple-negative breast cancer cells through apoptotic induction. Biochem Pharmacol. 2020 Aug;178:114053. doi: 10.1016/j.bcp.2020.114053. Epub 2020 May 23. PubMed
Stolze LK, Conklin AC, Whalen MB, Lpez Rodrguez M, unap K, Selvarajan I, Toropainen A, rd T, Li J, Eshghi A, Solomon AE, Fang Y, Kaikkonen MU, Romanoski CE. Systems Genetics in Human Endothelial Cells Identifies Non-coding Variants Modifying Enhancers, Expression, and Complex Disease Traits. Am J Hum Genet. 2020 Jun 4;106(6):748-763. doi
Bumm CV, Folwaczny M, Wlfle UC. Necrotizing periodontitis or medication-related osteonecrosis of the jaw (MRONJ) in a patient receiving Bemcentinib-a case report. Oral Maxillofac Surg. 2020 Sep;24(3):353-358. doi: 10.1007/s10006-020-00851-w. Epub 2020 May 21. PubMed
McDaniel NK, Iida M, Nickel KP, Longhurst CA, Fischbach SR, Rodems TS, Kranjac CA, Bo AY, Luo Q, Gallagher MM, Welke NB, Mitchell KR, Schulz AE, Eckers JC, Hu R, Salgia R, Hong S, Bruce JY, Kimple RJ, Wheeler DL. AXL Mediates Cetuximab and Radiation Resistance Through Tyrosine 821 and the c-ABL Kinase Pathway in Head and Neck Cancer. Clin Cancer Res. 2020 May 21. doi: 10.1158/1078-0432.CCR-19-3142. [Epub ahead of print] PubMed
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Kong L, Lu X, Chen X, Wu Y, Zhang Y, Shi H, Li J. Qigesan inhibits esophageal cancer cell invasion and migration by inhibiting Gas6/Axl-induced epithelial-mesenchymal transition. Aging (Albany NY). 2020 May 20;12(10):9714-9725. doi
Bakstytė V, Šniurevičiūtė L, Šimienė E, Skruodytė J, Janulevičienė I. Determination of Referential Rates for Optical Coherence Tomography and Optical Coherence Tomography Angiography Flow Deficits in the Macular Choriocapillaris in Ophthalmologically Healthy Children. Medicina (Kaunas). 2020 May 16;56(5). pii: E238. doi
Shu S, Wu HJ, Ge JY, Zeid R, Harris IS, Jovanović B, Murphy K, Wang B, Qiu X, Endress JE, Reyes J, Lim K, Font-Tello A, Syamala S, Xiao T, Reddy Chilamakuri CS, Papachristou EK, D'Santos C, Anand J, Hinohara K, Li W, McDonald TO, Luoma A, Modiste RJ, Nguyen QD, Michel B, Cejas P, Kadoch C, Jaffe JD, Wucherpfennig KW, Qi J, Liu XS, Long H, Brown M, Carroll JS, Brugge JS, Bradner J, Michor F, Polyak K. Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer. Mol Cell. 2020 Jun 18;78(6):1096-1113.e8. doi
Bejdic N, Biscevic A, Pjano MA, Ivezic B. Incidence of Keratoconus in Refractive Surgery Population of Vojvodina - Single Center Study. Mater Sociomed. 2020 Mar;32(1):46-49. doi
Wang J, Li Y, Wang P, Han G, Zhang T, Chang J, Yin R, Shan Y, Wen J, Xie X, Feng M, Wang Q, Hu J, Cheng Y, Zhang T, Li Y, Gao Z, Guo C, Wang J, Liang J, Cui M, Gao K, Chai J, Liu W, Cheng H, Li L, Zhou F, Liu L, Luo Y, Li S, Zhang H. Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis. Cell Stem Cell. 2020 Jul 2;27(1):81-97.e8. doi
Rocha-Brito KJP, Fonseca EMB, Oliveira BGF, Ftima , Ferreira-Halder CV. Calix[6]arene diminishes receptor tyrosine kinase lifespan in pancreatic cancer cells and inhibits their migration and invasion efficiency. Bioorg Chem. 2020 Jul;100:103881. doi
Rao L, Mak VCY, Zhou Y, Zhang D, Li X, Fung CCY, Sharma R, Gu C, Lu Y, Tipoe GL, Cheung ANY, Mills GB, Cheung LWT. p85β regulates autophagic degradation of AXL to activate oncogenic signaling. Nat Commun. 2020 May 8;11(1):2291. doi: 10.1038/s41467-020-16061-7. PubMed
Henriquez MA, Ziga-Iracheta R, Camino-Quezada M, Camargo-Acua J, Ruiz-Montenegro K, Izquierdo L Jr. Effectiveness and agreement of three optical biometers in measuring axial length in the eyes of patients with mature cataracts. J Cataract Refract Surg. 2020 May 4. doi: 10.1097/j.jcrs.0000000000000237. [Epub ahead of print] PubMed
Zhao W, Fan J, Kulic I, Koh C, Clark A, Meuller J, Engkvist O, Barichievy S, Raynoschek C, Hicks R, Maresca M, Wang Q, Brown DG, Lok A, Parro C, Robert J, Chou HY, Zuhl AM, Wood MW, Brandon NJ, Wellington CL. Axl receptor tyrosine kinase is a regulator of apolipoprotein E. Mol Brain. 2020 May 4;13(1):66. doi: 10.1186/s13041-020-00609-1. PubMed
Shibata T, Makino A, Ogata R, Nakamura S, Ito T, Nagata K, Terauchi Y, Oishi T, Fujieda M, Takahashi Y, Ato M. Respiratory syncytial virus infection exacerbates pneumococcal pneumonia via Gas6/Axl-mediated macrophage polarization. J Clin Invest. 2020 Jun 1;130(6):3021-3037. doi
Pontara A, Paolino G, Gregorc V, Mercuri SR, Bulotta A, Bearzi P, Doglioni C, Rizzo N. Immunohistochemical Evaluation and Clinicopathological Correlation of Mer and Axl Tyrosine Kinase TAM Receptors in Cutaneous Melanoma. Dermatol Pract Concept. 2020 Apr 3;10(2):e2020029. doi
Ibrahim AM, Gray Z, Gomes AM, Myers L, Behbod F, Machado HL. Gas6 expression is reduced in advanced breast cancers. NPJ Precis Oncol. 2020 Apr 24;4:9. doi: 10.1038/s41698-020-0116-z. eCollection 2020. PubMed
Anselmi G, Vaivode K, Dutertre CA, Bourdely P, Missolo-Koussou Y, Newell E, Hickman O, Wood K, Saxena A, Helft J, Ginhoux F, Guermonprez P. Engineered niches support the development of human dendritic cells in humanized mice. Nat Commun. 2020 Apr 28;11(1):2054. doi
Reed DR, Sen JM, Pierce EJ, Elsarrag RZ, K Keng M. Gilteritinib
Kurata A, Tachibana Y, Takahashi T, Horiba N. Novel AXL-specific inhibitor ameliorates kidney dysfunction through the inhibition of epithelial-to-mesenchymal transition of renal tubular cells. PLoS One. 2020 Apr 23;15(4):e0232055. doi
Du W, Sun L, Liu T, Zhu J, Zeng Y, Zhang Y, Wang X, Liu Z, Huang JA. The miR‑625‑3p/AXL axis induces non‑T790M acquired resistance to EGFR‑TKI via activation of the TGF‑β/Smad pathway and EMT in EGFR‑mutant non‑small cell lung cancer. Oncol Rep. 2020 Jul;44(1):185-195. doi
Li Y, Fan H, Sun J, Ni M, Zhang L, Chen C, Hong X, Fang F, Zhang W, Ma P. Circular RNA expression profile of Alzheimer's disease and its clinical significance as biomarkers for the disease risk and progression. Int J Biochem Cell Biol. 2020 Jun;123:105747. doi
Lee JH, Shklovskaya E, Lim SY, Carlino MS, Menzies AM, Stewart A, Pedersen B, Irvine M, Alavi S, Yang JYH, Strbenac D, Saw RPM, Thompson JF, Wilmott JS, Scolyer RA, Long GV, Kefford RF, Rizos H. Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibition. Nat Commun. 2020 Apr 20;11(1):1897. doi
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Umemura S, Sowa Y, Iizumi Y, Kitawaki J, Sakai T. Synergistic effect of the inhibitors of RAF/MEK and AXL on KRAS-mutated ovarian cancer cells with high AXL expression. Cancer Sci. 2020 Jun;111(6):2052-2061. doi
Meng J, He W, Rong X, Miao A, Lu Y, Zhu X. Decentration and tilt of plate-haptic multifocal intraocular lenses in myopic eyes. Eye Vis (Lond). 2020 Apr 7;7:17. doi
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Personeni N, Pressiani T, Bozzarelli S, Rimassa L. Targeted agents for second-line treatment of advanced hepatocellular carcinoma. World J Gastrointest Oncol. 2019 Oct 15;11(10):788-803. doi
Liphaus BL, Lima L, Palmeira P, Silva CA, Goldenstein-Schainberg C, Carneiro-Sampaio M. Increased sMer, but not sAxl, sTyro3, and Gas6 relate with active disease in juvenile systemic lupus erythematosus. Clin Rheumatol. 2020 Feb;39(2):509-514. doi
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Yun MR, Choi HM, Lee YW, Joo HS, Park CW, Choi JW, Kim DH, Kang HN, Pyo KH, Shin EJ, Shim HS, Soo RA, Yang JC, Lee SS, Chang H, Kim MH, Hong MH, Kim HR, Cho BC. Targeting YAP to overcome acquired resistance to ALK inhibitors in ALK-rearranged lung cancer. EMBO Mol Med. 2019 Dec;11(12):e10581. doi: 10.15252/emmm.201910581. Epub 2019 Oct 21. PubMed
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Schrder S, Langenbucher A, Schrecker J. Comparison of corneal elevation and pachymetry measurements made by two state of the art corneal tomographers with different measurement principles. PLoS One. 2019 Oct 16;14(10):e0223770. doi: 10.1371/journal.pone.0223770. eCollection 2019. PubMed
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Bonifacio L, Dodds M, Prohaska D, Moss A, Giaccia A, Tabibiazar R, McIntyre G. Target-Mediated Drug Disposition Pharmacokinetic/Pharmacodynamic Model-Informed Dose Selection for the First-in-Human Study of AVB-S6-500. Clin Transl Sci. 2020 Jan;13(1):204-211. doi
Jung J, Yang K, Kim HJ, Lee YJ, Kim M, Choi YH, Kang JL. RhoA-Dependent HGF and c-Met Mediate Gas6-Induced Inhibition of Epithelial-Mesenchymal Transition, Migration, and Invasion of Lung Alveolar Epithelial Cells. Biomolecules. 2019 Oct 4;9(10). pii
Xiao Y, Zhao H, Tian L, Nolley R, Diep AN, Ernst A, Fuh KC, Miao YR, von Eyben R, Leppert JT, Brooks JD, Peehl DM, Giaccia AJ, Rankin EB. S100A10 Is a Critical Mediator of GAS6/AXL-Induced Angiogenesis in Renal Cell Carcinoma. Cancer Res. 2019 Nov 15;79(22):5758-5768. doi
Dihingia A, Ozah D, Borah T, Kalita J, Manna P. Gamma-glutamyl-carboxylated Gas6 mediates positive role of vitamin K on lowering hyperglycemia in type 2 diabetes. Ann N Y Acad Sci. 2020 Feb;1462(1):104-117. doi
Smirne C, Rigamonti C, De Benedittis C, Sainaghi PP, Bellan M, Burlone ME, Castello LM, Avanzi GC. Gas6/TAM Signaling Components as Novel Biomarkers of Liver Fibrosis. Dis Markers. 2019 Sep 8;2019:2304931. doi
Wang G, Dong Y, Liu H, Ji N, Cao J, Liu A, Tang X, Ren Y. Loss of miR-873 contributes to gemcitabine resistance in triple-negative breast cancer via targeting ZEB1. Oncol Lett. 2019 Oct;18(4):3837-3844. doi
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Ma L, She C, Shi Q, Yin Q, Ji X, Wang Y, Fan Y, Kong X, Li P, Sun Z, Zhang X, Zhang Z, Wang J, Wang T, Xu Y, Li W. TNFα inhibitor C87 sensitizes EGFRvIII transfected glioblastoma cells to gefitinib by a concurrent blockade of TNFα signaling. Cancer Biol Med. 2019 Aug;16(3):606-617. doi: 10.20892/j.issn.2095-3941.2019.0011. PubMed
Kim SM, Park M, Yee SM, Ji KY, Lee EH, Nguyen TV, Nguyen TH, Jang J, Kim EM, Choi HR, Yun CH, Kang HS. Axl is a key regulator of intestinal γδ T-cell homeostasis. FASEB J. 2019 Dec;33(12):13386-13397. doi
Ahmadi R, Sepehri B, Ghavami R. Development linear and non-linear QSAR models for predicting AXL kinase inhibitory activity of N-[4-(quinolin-4-yloxy)phenyl]benzenesulfonamides. J Recept Signal Transduct Res. 2019 Jun;39(3):264-275. doi
Lee N, Jang WJ, Seo JH, Lee S, Jeong CH. 2-Deoxy-d-Glucose-Induced Metabolic Alteration in Human Oral Squamous SCC15 Cells
Chirino LM, Kumar S, Okumura M, Sterner DE, Mattern M, Butt TR, Kambayashi T. TAM receptors attenuate murine NK-cell responses via E3 ubiquitin ligase Cbl-b. Eur J Immunol. 2020 Jan;50(1):48-55. doi
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Li M, Ye J, Zhao G, Hong G, Hu X, Cao K, Wu Y, Lu Z. Gas6 attenuates lipopolysaccharide‑induced TNF‑α expression and apoptosis in H9C2 cells through NF‑κB and MAPK inhibition via the Axl/PI3K/Akt pathway. Int J Mol Med. 2019 Sep;44(3):982-994. doi
Thakur R, Laye JP, Lauss M, Diaz JMS, O'Shea SJ, Poźniak J, Filia A, Harland M, Gascoyne J, Randerson-Moor JA, Chan M, Mell T, Jönsson G, Bishop DT, Newton-Bishop J, Barrett JH, Nsengimana J. Transcriptomic Analysis Reveals Prognostic Molecular Signatures of Stage I Melanoma. Clin Cancer Res. 2019 Dec 15;25(24):7424-7435. doi
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Shi H, Sun Y, He M, Yang X, Hamada M, Fukunaga T, Zhang X, Chang C. Targeting the TR4 nuclear receptor-mediated lncTASR/AXL signaling with tretinoin increases the sunitinib sensitivity to better suppress the RCC progression. Oncogene. 2020 Jan;39(3):530-545. doi
Da C, Zhang D, Stashko M, Vasileiadi E, Parker RE, Minson KA, Huey MG, Huelse JM, Hunter D, Gilbert TSK, Norris-Drouin J, Miley M, Herring LE, Graves LM, DeRyckere D, Earp HS, Graham DK, Frye SV, Wang X, Kireev D. Data-Driven Construction of Antitumor Agents with Controlled Polypharmacology. J Am Chem Soc. 2019 Oct 2;141(39):15700-15709. doi
Jimbo T, Hatanaka M, Komatsu T, Taira T, Kumazawa K, Maeda N, Suzuki T, Ota M, Haginoya N, Isoyama T, Fujiwara K. DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model. Oncotarget. 2019 Aug 27;10(50):5152-5167. doi
Terry S, Abdou A, Engelsen AST, Buart S, Dessen P, Corgnac S, Collares D, Meurice G, Gausdal G, Baud V, Saintigny P, Lorens JB, Thiery JP, Mami-Chouaib F, Chouaib S. AXL Targeting Overcomes Human Lung Cancer Cell Resistance to NK- and CTL-Mediated Cytotoxicity. Cancer Immunol Res. 2019 Nov;7(11):1789-1802. doi: 10.1158/2326-6066.CIR-18-0903. Epub 2019 Sep 5. PubMed
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Li Z, Wang Z, Tang Y, Lu X, Chen J, Dong Y, Wu B, Wang C, Yang L, Guo Z, Xue M, Lu S, Wei W, Shi Q. Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics. Nat Commun. 2019 Aug 26;10(1):3856. doi
Holtzhausen A, Harris W, Ubil E, Hunter DM, Zhao J, Zhang Y, Zhang D, Liu Q, Wang X, Graham DK, Frye SV, Earp HS. TAM Family Receptor Kinase Inhibition Reverses MDSC-Mediated Suppression and Augments Anti-PD-1 Therapy in Melanoma. Cancer Immunol Res. 2019 Oct;7(10):1672-1686. doi
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Fukumitsu H, Camps VJ, Piero DP. Intrasession Repeatability of Biometric Measurements Obtained with a Low-Coherence Interferometry System in Pseudophakic Eyes. Curr Eye Res. 2020 Feb;45(2):221-226. doi
Yang H, Liang SQ, Xu D, Yang Z, Marti TM, Gao Y, Kocher GJ, Zhao H, Schmid RA, Peng RW. HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer. Oncogenesis. 2019 Aug 20;8(9):45. doi
Lin H, Hong Y, Huang B, Liu X, Zheng J, Qiu S. Vimentin Overexpressions Induced by Cell Hypoxia Promote Vasculogenic Mimicry by Renal Cell Carcinoma Cells. Biomed Res Int. 2019 Jul 21;2019:7259691. doi
Chen YC, Chen SN. Foveal microvasculature, refractive errors, optical biometry and their correlations in school-aged children with retinopathy of prematurity after intravitreal antivascular endothelial growth factors or laser photocoagulation. Br J Ophthalmol. 2020 May;104(5):691-696. doi: 10.1136/bjophthalmol-2019-314610. Epub 2019 Aug 16. PubMed
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Zhu H, Jin YM, Lyu XM, Fan LM, Wu F. Long noncoding RNA H19 regulates HIF-1α/AXL signaling through inhibiting miR-20b-5p in endometrial cancer. Cell Cycle. 2019 Oct;18(19):2454-2464. doi
Veeranki OL, Tong Z, Dokey R, Mejia A, Zhang J, Qiao Y, Singh PK, Katkhuda R, Mino B, Tailor R, Canales JR, Bassett R, Ajani J, Wu JY, Kopetz S, Blum M, Hofstetter W, Tetzlaff M, Krishnan S, Lin SH, Maru D. Targeting cyclin-dependent kinase 9 by a novel inhibitor enhances radiosensitization and identifies Axl as a novel downstream target in esophageal adenocarcinoma. Oncotarget. 2019 Jul 23;10(45):4703-4718. doi
Dolan M, Mastri M, Tracz A, Christensen JG, Chatta G, Ebos JML. Enhanced efficacy of sitravatinib in metastatic models of antiangiogenic therapy resistance. PLoS One. 2019 Aug 1;14(8):e0220101. doi: 10.1371/journal.pone.0220101. eCollection 2019. PubMed
Kawasaki Y, Miyamoto M, Oda T, Matsumura K, Negishi L, Nakato R, Suda S, Yokota N, Shirahige K, Akiyama T. The novel lncRNA CALIC upregulates AXL to promote colon cancer metastasis. EMBO Rep. 2019 Aug;20(8):e47052. doi: 10.15252/embr.201847052. Epub 2019 Jul 29. PubMed
Hirschi KM, Tsai KYF, Davis T, Clark JC, Knowlton MN, Bikman BT, Reynolds PR, Arroyo JA. Growth arrest-specific protein-6/AXL signaling induces preeclampsia in rats†. Biol Reprod. 2020 Feb 12;102(1):199-210. doi: 10.1093/biolre/ioz140. PubMed
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Peng CK, Wu CP, Lin JY, Peng SC, Lee CH, Huang KL, Shen CH. Gas6/Axl signaling attenuates alveolar inflammation in ischemia-reperfusion-induced acute lung injury by up-regulating SOCS3-mediated pathway. PLoS One. 2019 Jul 18;14(7):e0219788. doi
Xiang Z, Li J, Song S, Wang J, Cai W, Hu W, Ji J, Zhu Z, Zang L, Yan R, Yu Y. A positive feedback between IDO1 metabolite and COL12A1 via MAPK pathway to promote gastric cancer metastasis. J Exp Clin Cancer Res. 2019 Jul 17;38(1):314. doi
Strange DP, Jiyarom B, Pourhabibi Zarandi N, Xie X, Baker C, Sadri-Ardekani H, Shi PY, Verma S. Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells. mBio. 2019 Jul 16;10(4). pii
Bhme I, Bosserhoff A. Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells. Pigment Cell Melanoma Res. 2020 Jan;33(1):41-51. doi
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Fujino N, Brand OJ, Morgan DJ, Fujimori T, Grabiec AM, Jagger CP, Maciewicz RA, Yamada M, Itakura K, Sugiura H, Ichinose M, Hussell T. Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases. J Exp Med. 2019 Sep 2;216(9):2184-2201. doi
Wang ZY, Yang WL, Li DJ, Chen W, Zhao Q, Li YF, Cui R, Shen L, Xian JF. [Comparison of biometry with the Pentacam AXL, IOLMaster 700 and IOLMaster 500 in cataract patients]. Zhonghua Yan Ke Za Zhi. 2019 Jul 11;55(7):515-521. doi: 10.3760/cma.j.issn.0412-4081.2019.07.007. Chinese. PubMed
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Monmeesil P, Fungfuang W, Tulayakul P, Pongchairerk U. The effects of astaxanthin on liver histopathology and expression of superoxide dismutase in rat aflatoxicosis. J Vet Med Sci. 2019 Aug 24;81(8):1162-1172. doi: 10.1292/jvms.18-0690. Epub 2019 Jul 3. PubMed
Woo SM, Min KJ, Seo SU, Kim S, Kubatka P, Park JW, Kwon TK. Axl Inhibitor R428 Enhances TRAIL-Mediated Apoptosis Through Downregulation of c-FLIP and Survivin Expression in Renal Carcinoma. Int J Mol Sci. 2019 Jul 2;20(13). pii: E3253. doi
Nam RK, Benatar T, Wallis CJD, Kobylecky E, Amemiya Y, Sherman C, Seth A. MicroRNA-139 is a predictor of prostate cancer recurrence and inhibits growth and migration of prostate cancer cells through cell cycle arrest and targeting IGF1R and AXL. Prostate. 2019 Sep;79(12):1422-1438. doi
Peeters MJW, Dulkeviciute D, Draghi A, Ritter C, Rahbech A, Skadborg SK, Seremet T, Carnaz Simes AM, Martinenaite E, Halldrsdttir HR, Andersen MH, Olofsson GH, Svane IM, Rasmussen LJ, Met , Becker JC, Donia M, Desler C, Thor Straten P. MERTK Acts as a Costimulatory Receptor on Human CD8(+) T Cells. Cancer Immunol Res. 2019 Sep;7(9):1472-1484. doi
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Alampi DM, Ciusani E, Carenini N, Corna E, Gatti L, Corno C. AXL Downstream Targeting Unravels Synergistic Drug Combinations in Ovarian Carcinoma Cells. Anticancer Res. 2019 Jul;39(7):3803-3808. doi
Shajari M, Kolb CM, Mayer WJ, Agha B, Steinwender G, Dirisamer M, Priglinger S, Kohnen T, Schmack I. Characteristics of preoperative and postoperative astigmatism in patients having Descemet membrane endothelial keratoplasty. J Cataract Refract Surg. 2019 Jul;45(7):1001-1006. doi
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Yan J, Xu C, Li Y, Tang B, Xie S, Hong T, Zeng E. Long non-coding RNA LINC00526 represses glioma progression via forming a double negative feedback loop with AXL. J Cell Mol Med. 2019 Aug;23(8):5518-5531. doi
Garrido-Hermosilla AM, Mndez-Muros M, Gutirrez-Snchez E, Morales-Portillo C, Daz-Granda MJ, Esteban-Gonzlez E, Relimpio-Lpez I, Martnez-Brocca MA, Rodrguez-de-la-Ra-Franch E. Renal function and choroidal thickness using swept-source optical coherence tomography in diabetic patients. Int J Ophthalmol. 2019 Jun 18;12(6):985-989. doi
Zheng SZ, Sun P, Wang JP, Liu Y, Gong W, Liu J. MiR-34a overexpression enhances the inhibitory effect of doxorubicin on HepG2 cells. World J Gastroenterol. 2019 Jun 14;25(22):2752-2762. doi
Najafov A, Mookhtiar AK, Luu HS, Ordureau A, Pan H, Amin PP, Li Y, Lu Q, Yuan J. TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL. Mol Cell. 2019 Aug 8;75(3):457-468.e4. doi
Li XL, Zhang B, Sun MJ, Bao CC, Yuan BY, Xie QF, Wang LJ, Wang MX. Mechanism of gut microbiota and Axl/SOCS3 in experimental autoimmune encephalomyelitis. Biosci Rep. 2019 Jul 2;39(7). pii
Sun ZG, Liu JH, Zhang JM, Qian Y. Research Progress of Axl Inhibitors. Curr Top Med Chem. 2019;19(15):1338-1349. doi
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Lee AJ, Mian F, Poznanski SM, Stackaruk M, Chan T, Chew MV, Ashkar AA. Type I Interferon Receptor on NK Cells Negatively Regulates Interferon-γ Production. Front Immunol. 2019 Jun 4;10:1261. doi
Personeni N, Pressiani T, Rimassa L. Cabozantinib in patients with hepatocellular carcinoma failing previous treatment with sorafenib. Future Oncol. 2019 Jul;15(21):2449-2462. doi
Kim J, Lim DH, Han SH, Chung TY. Predictive factors associated with axial length growth and myopia progression in orthokeratology. PLoS One. 2019 Jun 12;14(6):e0218140. doi
Duan Y, Hu B, Qiao C, Luo L, Li X, Wang J, Liu H, Zhou T, Shen B, Lv M, Feng J. Engineered AXL(-ECD)-Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration. Oncol Lett. 2019 Jun;17(6):5784-5792. doi: 10.3892/ol.2019.10255. Epub 2019 Apr 15. PubMed
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Yang S, Zhang X, Qu H, Qu B, Yin X, Zhao H. Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway. Cancer Gene Ther. 2020 May;27(5):368-377. doi: 10.1038/s41417-019-0098-6. Epub 2019 Jun 11. PubMed
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Batlle M, Castillo N, Alcarraz A, Sarvari S, Sangesa G, Cristbal H, Garca de Frutos P, Sitges M, Mont L, Guasch E. Axl expression is increased in early stages of left ventricular remodeling in an animal model with pressure-overload. PLoS One. 2019 Jun 10;14(6):e0217926. doi
Lauter M, Weber A, Torka R. Targeting of the AXL receptor tyrosine kinase by small molecule inhibitor leads to AXL cell surface accumulation by impairing the ubiquitin-dependent receptor degradation. Cell Commun Signal. 2019 Jun 6;17(1):59. doi
Wen L, Zheng Y, Wen X, Zhang Y, Zeng W. Increased expression of long noncoding RNA GAS6-AS2 promotes proliferation and inhibits apoptosis of melanoma cells via upregulating GAS6 expression. IUBMB Life. 2019 Oct;71(10):1503-1514. doi
Liu YN, Tsai MF, Wu SG, Chang TH, Tsai TH, Gow CH, Chang YL, Shih JY. Acquired resistance to EGFR tyrosine kinase inhibitors is mediated by the reactivation of STC2/JUN/AXL signaling in lung cancer. Int J Cancer. 2019 Sep 15;145(6):1609-1624. doi
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Sun X, Guan H, Peng S, Zhao Y, Zhang L, Wang X, Li C, Shan Z, Teng W. Growth arrest-specific protein 6 (Gas6) attenuates inflammatory injury and apoptosis in iodine-induced NOD.H-2(h4) mice. Int Immunopharmacol. 2019 Aug;73:333-342. doi: 10.1016/j.intimp.2019.04.038. Epub 2019 May 23. PubMed
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Hsu CC, Hsieh PM, Chen YS, Lo GH, Lin HY, Dai CY, Huang JF, Chuang WL, Chen YL, Yu ML, Lin CW. Axl and autophagy LC3 expression in tumors is strongly associated with clinical prognosis of hepatocellular carcinoma patients after curative resection. Cancer Med. 2019 Jul;8(7):3453-3463. doi
Tanaka H, Sakagami H, Kaneko N, Konagai S, Yamamoto H, Matsuya T, Yuri M, Yamanaka Y, Mori M, Takeuchi M, Koshio H, Hirano M, Kuromitsu S. Mutant-Selective Irreversible EGFR Inhibitor, Naquotinib, Inhibits Tumor Growth in NSCLC Models with EGFR-Activating Mutations, T790M Mutation, and AXL Overexpression. Mol Cancer Ther. 2019 Aug;18(8):1366-1373. doi
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Suresh D, Zambre A, Mukherjee S, Ghoshdastidar S, Jiang Y, Joshi T, Upendran A, Kannan R. Silencing AXL by covalent siRNA-gelatin-antibody nanoconjugate inactivates mTOR/EMT pathway and stimulates p53 for TKI sensitization in NSCLC. Nanomedicine. 2019 Aug;20:102007. doi
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Wu N, Huang Y, Zou Z, Gimenez-Capitan A, Yu L, Hu W, Zhu L, Sun X, Sanchez JJ, Guan W, Liu B, Rosell R, Wei J. High BIM mRNA levels are associated with longer survival in advanced gastric cancer. Oncol Lett. 2017 Mar;13(3):1826-1834. doi
Patel RB, Li T, Liao Z, Jaldeepbhai JA, Perera HAPNV, Muthukuda SK, Dhirubhai DH, Singh V, Du X, Yang J. Recent translational research into targeted therapy for liposarcoma. Stem Cell Investig. 2017 Mar 15;4:21. doi: 10.21037/sci.2017.02.09. eCollection 2017. Review. PubMed
Seike M, Kim CH, Zou F, Noro R, Chiba M, Ishikawa A, Κunugi S, Kubota K, Gemma A. AXL and GAS6 co-expression in lung adenocarcinoma as a prognostic classifier. Oncol Rep. 2017 Jun;37(6):3261-3269. doi
Yin Z, Raj D, Saiepour N, Van Dam D, Brouwer N, Holtman IR, Eggen BJL, Möller T, Tamm JA, Abdourahman A, Hol EM, Kamphuis W, Bayer TA, De Deyn PP, Boddeke E. Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease. Neurobiol Aging. 2017 Jul;55:115-122. doi: 10.1016/j.neurobiolaging.2017.03.021. Epub 2017 Mar 27. PubMed
Kelley RK, Verslype C, Cohn AL, Yang TS, Su WC, Burris H, Braiteh F, Vogelzang N, Spira A, Foster P, Lee Y, Van Cutsem E. Cabozantinib in hepatocellular carcinoma
Lee EH, Kim EM, Ji KY, Park AR, Choi HR, Lee HY, Kim SM, Chung BY, Park CH, Choi HJ, Ko YH, Bai HW, Kang HS. Axl acts as a tumor suppressor by regulating LIGHT expression in T lymphoma. Oncotarget. 2017 Mar 28;8(13):20645-20655. doi: 10.18632/oncotarget.15830. PubMed
Hastings AK, Yockey LJ, Jagger BW, Hwang J, Uraki R, Gaitsch HF, Parnell LA, Cao B, Mysorekar IU, Rothlin CV, Fikrig E, Diamond MS, Iwasaki A. TAM Receptors Are Not Required for Zika Virus Infection in Mice. Cell Rep. 2017 Apr 18;19(3):558-568. doi
Blake A, Dragan M, Tirona RG, Hardy DB, Brackstone M, Tuck AB, Babwah AV, Bhattacharya M. G protein-coupled KISS1 receptor is overexpressed in triple negative breast cancer and promotes drug resistance. Sci Rep. 2017 Apr 19;7:46525. doi
Zhu XJ, He WW, Du Y, Qian DJ, Dai JH, Lu Y. [Intraocular lens power calculation for high myopic eyes with cataract
Grabiec AM, Denny N, Doherty JA, Happonen KE, Hankinson J, Connolly E, Fife ME, Fujimori T, Fujino N, Goenka A, Holden S, Tavernier G, Shah R, Cook PC, MacDonald AS, Niven RM, Dahlbck B, Fowler SJ, Simpson A, Hussell T. Diminished airway macrophage expression of the Axl receptor tyrosine kinase is associated with defective efferocytosis in asthma. J Allergy Clin Immunol. 2017 Oct;140(4):1144-1146.e4. doi
Kozar I, Cesi G, Margue C, Philippidou D, Kreis S. Impact of BRAF kinase inhibitors on the miRNomes and transcriptomes of melanoma cells. Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt B):2980-2992. doi: 10.1016/j.bbagen.2017.04.005. Epub 2017 Apr 10. PubMed
Li L, Cai S, Liu S, Feng H, Zhang J. Bioinformatics analysis to screen the key prognostic genes in ovarian cancer. J Ovarian Res. 2017 Apr 13;10(1):27. doi: 10.1186/s13048-017-0323-6. PubMed
Corno C, Gatti L, Arrighetti N, Carenini N, Zaffaroni N, Lanzi C, Perego P. Axl molecular targeting counteracts aggressiveness but not platinum-resistance of ovarian carcinoma cells. Biochem Pharmacol. 2017 Jul 15;136:40-50. doi: 10.1016/j.bcp.2017.04.002. Epub 2017 Apr 9. PubMed
Huang RY, Antony J, Tan TZ, Tan DS. Targeting the AXL signaling pathway in ovarian cancer. Mol Cell Oncol. 2016 Nov 28;4(2):e1263716. doi: 10.1080/23723556.2016.1263716. eCollection 2017. PubMed
Kwon J, Sung KR, Park JM. Myopic glaucomatous eyes with or without optic disc shape alteration
Qiu C, Zheng H, Tao H, Yu W, Jiang X, Li A, Jin H, Lv A, Li H. Vitamin K2 inhibits rat vascular smooth muscle cell calcification by restoring the Gas6/Axl/Akt anti-apoptotic pathway. Mol Cell Biochem. 2017 Sep;433(1-2):149-159. doi
Petruzzi MN, Cherubini K, Salum FG, de Figueiredo MA. Role of tumour-associated macrophages in oral squamous cells carcinoma progression
Ohshima K, Hatakeyama K, Nagashima T, Watanabe Y, Kanto K, Doi Y, Ide T, Shimoda Y, Tanabe T, Ohnami S, Ohnami S, Serizawa M, Maruyama K, Akiyama Y, Urakami K, Kusuhara M, Mochizuki T, Yamaguchi K. Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors. Sci Rep. 2017 Apr 4;7(1):641. doi
Evans AL, Blackburn JWD, Taruc K, Kipp A, Dirk BS, Hunt NR, Barr SD, Dikeakos JD, Heit B. Antagonistic Coevolution of MER Tyrosine Kinase Expression and Function. Mol Biol Evol. 2017 Jul 1;34(7):1613-1628. doi: 10.1093/molbev/msx102. PubMed
Shin CH, Robinson JP, Sonnen JA, Welker AE, Yu DX, VanBrocklin MW, Holmen SL. HBEGF promotes gliomagenesis in the context of Ink4a/Arf and Pten loss. Oncogene. 2017 Aug 10;36(32):4610-4618. doi
Jiang L, Hermeking H. miR-34a and miR-34b/c Suppress Intestinal Tumorigenesis. Cancer Res. 2017 May 15;77(10):2746-2758. doi: 10.1158/0008-5472.CAN-16-2183. Epub 2017 Mar 31. PubMed
Jin G, Wang Z, Wang J, Zhang L, Chen Y, Yuan P, Liu D. Expression of Axl and its prognostic significance in human breast cancer. Oncol Lett. 2017 Feb;13(2):621-628. doi
Xu L, Chen Y, Dutra-Clarke M, Mayakonda A, Hazawa M, Savinoff SE, Doan N, Said JW, Yong WH, Watkins A, Yang H, Ding LW, Jiang YY, Tyner JW, Ching J, Kovalik JP, Madan V, Chan SL, Mschen M, Breunig JJ, Lin DC, Koeffler HP. BCL6 promotes glioma and serves as a therapeutic target. Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3981-3986. doi
Wakelee HA, Gettinger S, Engelman J, Jnne PA, West H, Subramaniam DS, Leach J, Wax M, Yaron Y, Miles DR, Lara PN Jr. A phase Ib/II study of cabozantinib (XL184) with or without erlotinib in patients with non-small cell lung cancer. Cancer Chemother Pharmacol. 2017 May;79(5):923-932. doi: 10.1007/s00280-017-3283-z. Epub 2017 Mar 28. PubMed
Li F, Wang PR, Qu LB, Yi CH, Zhang FC, Tang XP, Zhang LG, Chen L. AXL is not essential for Zika virus infection in the mouse brain. Emerg Microbes Infect. 2017 Mar 29;6(3):e16. doi
Sel S, Stange J, Kaiser D, Kiraly L. Repeatability and agreement of Scheimpflug-based and swept-source optical biometry measurements. Cont Lens Anterior Eye. 2017 Oct;40(5):318-322. doi
Gibault F, Bailly F, Corvaisier M, Coevoet M, Huet G, Melnyk P, Cotelle P. Molecular Features of the YAP Inhibitor Verteporfin
Wu G, Ma Z, Hu W, Wang D, Gong B, Fan C, Jiang S, Li T, Gao J, Yang Y. Molecular insights of Gas6/TAM in cancer development and therapy. Cell Death Dis. 2017 Mar 23;8(3):e2700. doi
Gustafsson A, Fritz HKM, Dahlbck B. Gas6-Axl signaling in presence of Sunitinib is enhanced, diversified and sustained in renal tumor cells, resulting in tumor-progressive advantages. Exp Cell Res. 2017 Jun 1;355(1):47-56. doi: 10.1016/j.yexcr.2017.03.040. Epub 2017 Mar 19. PubMed
Erratum
Lu Y, Ye Y, Yang Q, Shi S. Single-cell RNA-sequence analysis of mouse glomerular mesangial cells uncovers mesangial cell essential genes. Kidney Int. 2017 Aug;92(2):504-513. doi
Salam AP, Rojek A, Dunning J, Horby PW. Clinical Trials of Therapeutics for the Prevention of Congenital Zika Virus Disease
Aguilera TA, Giaccia AJ. Molecular Pathways
Pagani I, Ghezzi S, Ulisse A, Rubio A, Turrini F, Garavaglia E, Candiani M, Castilletti C, Ippolito G, Poli G, Broccoli V, Panina-Bordignon P, Vicenzi E. Human Endometrial Stromal Cells Are Highly Permissive To Productive Infection by Zika Virus. Sci Rep. 2017 Mar 10;7:44286. doi
Kimani SG, Kumar S, Bansal N, Singh K, Kholodovych V, Comollo T, Peng Y, Kotenko SV, Sarafianos SG, Bertino JR, Welsh WJ, Birge RB. Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity. Sci Rep. 2017 Mar 8;7:43908. doi
Zhao GJ, Zheng JY, Bian JL, Chen LW, Dong N, Yu Y, Hong GL, Chandoo A, Yao YM, Lu ZQ. Growth Arrest-Specific 6 Enhances the Suppressive Function of CD4(+)CD25(+) Regulatory T Cells Mainly through Axl Receptor. Mediators Inflamm. 2017;2017:6848430. doi
Shajari M, Cremonese C, Petermann K, Singh P, Mller M, Kohnen T. Comparison of Axial Length, Corneal Curvature, and Anterior Chamber Depth Measurements of 2 Recently Introduced Devices to a Known Biometer. Am J Ophthalmol. 2017 Jun;178:58-64. doi
Choi YJ, Kim JH, Rho JK, Kim JS, Choi CM, Kim WS, Son J, Lee JC. AXL and MET receptor tyrosine kinases are essential for lung cancer metastasis. Oncol Rep. 2017 Apr;37(4):2201-2208. doi
Akalu YT, Rothlin CV, Ghosh S. TAM receptor tyrosine kinases as emerging targets of innate immune checkpoint blockade for cancer therapy. Immunol Rev. 2017 Mar;276(1):165-177. doi
Schoumacher M, Burbridge M. Key Roles of AXL and MER Receptor Tyrosine Kinases in Resistance to Multiple Anticancer Therapies. Curr Oncol Rep. 2017 Mar;19(3):19. doi
Liu H, Feng X, Ennis KN, Behrmann CA, Sarma P, Jiang TT, Kofuji S, Niu L, Stratton Y, Thomas HE, Yoon SO, Sasaki AT, Plas DR. Pharmacologic Targeting of S6K1 in PTEN-Deficient Neoplasia. Cell Rep. 2017 Feb 28;18(9):2088-2095. doi: 10.1016/j.celrep.2017.02.022. PubMed
Tannir NM, Schwab G, Grnwald V. Cabozantinib
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Zhu S, Liu G, Fu W, Hu J, Fu K, Jia W. Axl promotes the proliferation, invasion and migration of Wilms' tumor and can be used as a prognostic factor. Onco Targets Ther. 2017 Feb 16;10:955-963. doi
Malek R, Wang H, Taparra K, Tran PT. Therapeutic Targeting of Epithelial Plasticity Programs
Ruprecht B, Zaal EA, Zecha J, Wu W, Berkers CR, Kuster B, Lemeer S. Lapatinib Resistance in Breast Cancer Cells Is Accompanied by Phosphorylation-Mediated Reprogramming of Glycolysis. Cancer Res. 2017 Apr 15;77(8):1842-1853. doi
Yen SY, Chuang HM, Huang MH, Lin SZ, Chiou TW, Harn HJ. n-Butylidenephthalide Regulated Tumor Stem Cell Genes EZH2/AXL and Reduced Its Migration and Invasion in Glioblastoma. Int J Mol Sci. 2017 Feb 10;18(2). pii: E372. doi
Guo L, Deng Y, Fang L, Liu C, Guo T. Characterization of ocular biometrics and aqueous humor dynamics in primary angle closure suspects. Medicine (Baltimore). 2017 Feb;96(7):e6096. doi
Choueiri TK, Halabi S, Sanford BL, Hahn O, Michaelson MD, Walsh MK, Feldman DR, Olencki T, Picus J, Small EJ, Dakhil S, George DJ, Morris MJ. Cabozantinib Versus Sunitinib As Initial Targeted Therapy for Patients With Metastatic Renal Cell Carcinoma of Poor or Intermediate Risk
Fardo DW, Katsumata Y, Kauwe JSK, Deming Y, Harari O, Cruchaga C; Alzheimer's Disease Neuroimaging Initiative, Nelson PT. CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN. Exp Gerontol. 2017 Apr;90:83-89. doi
Corallo S, D'Argento E, Strippoli A, Basso M, Monterisi S, Rossi S, Cassano A, Barone CM. Treatment Options for EGFR T790M-Negative EGFR Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer. Target Oncol. 2017 Apr;12(2):153-161. doi
Kasikara C, Kumar S, Kimani S, Tsou WI, Geng K, Davra V, Sriram G, Devoe C, Nguyen KN, Antes A, Krantz A, Rymarczyk G, Wilczynski A, Empig C, Freimark B, Gray M, Schlunegger K, Hutchins J, Kotenko SV, Birge RB. Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression. Mol Cancer Res. 2017 Jun;15(6):753-764. doi: 10.1158/1541-7786.MCR-16-0350. Epub 2017 Feb 9. PubMed
Richard AS, Shim BS, Kwon YC, Zhang R, Otsuka Y, Schmitt K, Berri F, Diamond MS, Choe H. AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):2024-2029. doi
Husain H, Scur M, Murtuza A, Bui N, Woodward B, Kurzrock R. Strategies to Overcome Bypass Mechanisms Mediating Clinical Resistance to EGFR Tyrosine Kinase Inhibition in Lung Cancer. Mol Cancer Ther. 2017 Feb;16(2):265-272. doi: 10.1158/1535-7163.MCT-16-0105. Review. PubMed
Akkermann R, Aprico A, Perera AA, Bujalka H, Cole AE, Xiao J, Field J, Kilpatrick TJ, Binder MD. The TAM receptor Tyro3 regulates myelination in the central nervous system. Glia. 2017 Apr;65(4):581-591. doi
Li S, Guo Q, Zhu H, Li Z, Su Y, Dong B. Increased Mer and Axl receptor tyrosine kinase expression on glomeruli in lupus nephritis. Clin Rheumatol. 2017 May;36(5):1063-1070. doi
Abboud-Jarrous G, Priya S, Maimon A, Fischman S, Cohen-Elisha M, Czerninski R, Burstyn-Cohen T. Protein S drives oral squamous cell carcinoma tumorigenicity through regulation of AXL. Oncotarget. 2017 Feb 21;8(8):13986-14002. doi: 10.18632/oncotarget.14753. PubMed
Chen L, Xiang B, Wang X, Xiang C. Exosomes derived from human menstrual blood-derived stem cells alleviate fulminant hepatic failure. Stem Cell Res Ther. 2017 Jan 23;8(1):9. doi
Qu X, Liu J, Zhong X, Li X, Zhang Q. Role of AXL expression in non-small cell lung cancer. Oncol Lett. 2016 Dec;12(6):5085-5091. doi: 10.3892/ol.2016.5356. Epub 2016 Nov 7. PubMed
Daud A, Kluger HM, Kurzrock R, Schimmoller F, Weitzman AL, Samuel TA, Moussa AH, Gordon MS, Shapiro GI. Phase II randomised discontinuation trial of the MET/VEGF receptor inhibitor cabozantinib in metastatic melanoma. Br J Cancer. 2017 Feb 14;116(4):432-440. doi
El Bezawy R, De Cesare M, Pennati M, Deraco M, Gandellini P, Zuco V, Zaffaroni N. Antitumor activity of miR-34a in peritoneal mesothelioma relies on c-MET and AXL inhibition
Rausch K, Hackett BA, Weinbren NL, Reeder SM, Sadovsky Y, Hunter CA, Schultz DC, Coyne CB, Cherry S. Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus. Cell Rep. 2017 Jan 17;18(3):804-815. doi
Falletta P, Sanchez-Del-Campo L, Chauhan J, Effern M, Kenyon A, Kershaw CJ, Siddaway R, Lisle R, Freter R, Daniels MJ, Lu X, Tting T, Middleton M, Buffa FM, Willis AE, Pavitt G, Ronai ZA, Sauka-Spengler T, Hlzel M, Goding CR. Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma. Genes Dev. 2017 Jan 1;31(1):18-33. doi: 10.1101/gad.290940.116. Epub 2017 Jan 17. PubMed
Feneyrolles C, Guiet L, Singer M, Van Hijfte N, Dayd-Cazals B, Fauvel B, Chev G, Yasri A. Discovering novel 7-azaindole-based series as potent AXL kinase inhibitors. Bioorg Med Chem Lett. 2017 Feb 15;27(4):862-866. doi: 10.1016/j.bmcl.2017.01.015. Epub 2017 Jan 9. PubMed
Keung W, Boloor A, Brown J, Kiryanov A, Gangloff A, Lawson JD, Skene R, Hoffman I, Atienza J, Kahana J, De Jong R, Farrell P, Balakrishna D, Halkowycz P. Structure-based optimization of 1H-imidazole-2-carboxamides as Axl kinase inhibitors utilizing a Mer mutant surrogate. Bioorg Med Chem Lett. 2017 Feb 15;27(4):1099-1104. doi
Faizan MI, Abdullah M, Ali S, Naqvi IH, Ahmed A, Parveen S. Zika Virus-Induced Microcephaly and Its Possible Molecular Mechanism. Intervirology. 2016;59(3):152-158. doi
Meertens L, Labeau A, Dejarnac O, Cipriani S, Sinigaglia L, Bonnet-Madin L, Le Charpentier T, Hafirassou ML, Zamborlini A, Cao-Lormeau VM, Coulpier M, Miss D, Jouvenet N, Tabibiazar R, Gressens P, Schwartz O, Amara A. Axl Mediates ZIKA Virus Entry in Human Glial Cells and Modulates Innate Immune Responses. Cell Rep. 2017 Jan 10;18(2):324-333. doi
Yao CJ, Chow JM, Lin PC, Hu TS, Kuo HC, Huang JS, Bai KJ, Lai GM. Activation of p53/miR-34a Tumor Suppressor Axis by Chinese Herbal Formula JP-1 in A549 Lung Adenocarcinoma Cells. Evid Based Complement Alternat Med. 2016;2016:5989681. doi: 10.1155/2016/5989681. Epub 2016 Dec 18. PubMed
Gay CM, Balaji K, Byers LA. Giving AXL the axe
Vincent KM, Postovit LM. Investigating the utility of human melanoma cell lines as tumour models. Oncotarget. 2017 Feb 7;8(6):10498-10509. doi: 10.18632/oncotarget.14443. PubMed
Wu M, Lu S, Zhong J, Huang K, Zhang S. Protective Effects of Pterostilbene Against Myocardial Ischemia/Reperfusion Injury in Rats. Inflammation. 2017 Apr;40(2):578-588. doi
Fleming I. Annexing AXL
Nassar M, Tabib Y, Capucha T, Mizraji G, Nir T, Pevsner-Fischer M, Zilberman-Schapira G, Heyman O, Nussbaum G, Bercovier H, Wilensky A, Elinav E, Burstyn-Cohen T, Hovav AH. GAS6 is a key homeostatic immunological regulator of host-commensal interactions in the oral mucosa. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E337-E346. doi
Brand TM, Iida M, Corrigan KL, Braverman CM, Coan JP, Flanigan BG, Stein AP, Salgia R, Rolff J, Kimple RJ, Wheeler DL. The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor. Sci Signal. 2017 Jan 3;10(460). pii
Lee YJ, Lim T, Han MS, Lee SH, Baek SH, Nan HY, Lee C. Anticancer effect of luteolin is mediated by downregulation of TAM receptor tyrosine kinases, but not interleukin-8, in non-small cell lung cancer cells. Oncol Rep. 2017 Feb;37(2):1219-1226. doi
Lu Y, Wan J, Yang Z, Lei X, Niu Q, Jiang L, Passtoors WM, Zang A, Fraering PC, Wu F. Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells. FASEB J. 2017 Apr;31(4):1382-1397. doi
von Mssenhausen A, Brgelmann J, Billig H, Thewes B, Queisser A, Vogel W, Kristiansen G, Schrck A, Bootz F, Brossart P, Kirfel J, Perner S. Implication of the Receptor Tyrosine Kinase AXL in Head and Neck Cancer Progression. Int J Mol Sci. 2016 Dec 22;18(1). pii
Aguilera TA, Rafat M, Castellini L, Shehade H, Kariolis MS, Hui AB, Stehr H, von Eyben R, Jiang D, Ellies LG, Koong AC, Diehn M, Rankin EB, Graves EE, Giaccia AJ. Reprogramming the immunological microenvironment through radiation and targeting Axl. Nat Commun. 2016 Dec 23;7:13898. doi
Lim S, Chen B, Kariolis MS, Dimov IK, Baer TM, Cochran JR. Engineering High Affinity Protein-Protein Interactions Using a High-Throughput Microcapillary Array Platform. ACS Chem Biol. 2017 Feb 17;12(2):336-341. doi: 10.1021/acschembio.6b00794. Epub 2016 Dec 20. PubMed
Di Benedetto A, Mottolese M, Sperati F, Ercolani C, Di Lauro L, Pizzuti L, Vici P, Terrenato I, Shaaban AM, Humphries MP, Sundara-Rajan S, Barba M, Speirs V, De Maria R, Maugeri-Sacc M. Association between AXL, Hippo Transducers, and Survival Outcomes in Male Breast Cancer. J Cell Physiol. 2017 Aug;232(8):2246-2252. doi
Labots M, Gotink KJ, Dekker H, Azijli K, van der Mijn JC, Huijts CM, Piersma SR, Jimnez CR, Verheul HM. Evaluation of a tyrosine kinase peptide microarray for tyrosine kinase inhibitor therapy selection in cancer. Exp Mol Med. 2016 Dec 16;48(12):e279. doi
Peter SC, Mannu J, Mathur PP. In Silico Approach to Identify Potential Inhibitors for Axl-Gas6 Signaling. Methods Mol Biol. 2017;1549:221-229. PubMed
Subramanian M, Proto JD, Matsushima GK, Tabas I. Deficiency of AXL in Bone Marrow-Derived Cells Does Not Affect Advanced Atherosclerotic Lesion Progression. Sci Rep. 2016 Dec 13;6:39111. doi
de Polo A, Luo Z, Gerarduzzi C, Chen X, Little JB, Yuan ZM. AXL receptor signalling suppresses p53 in melanoma through stabilization of the MDMX-MDM2 complex. J Mol Cell Biol. 2017 Apr 1;9(2):154-165. doi
Lee CH, Hung YJ, Shieh YS, Chien CY, Hsu YJ, Lin CY, Chiang CF, Huang CL, Hsieh CH. Cilostazol inhibits uremic toxin-induced vascular smooth muscle cell dysfunction
Leconet W, Chentouf M, du Manoir S, Chevalier C, Sirvent A, At-Arsa I, Busson M, Jarlier M, Radosevic-Robin N, Theillet C, Chalbos D, Pasquet JM, Plegrin A, Larbouret C, Robert B. Therapeutic Activity of Anti-AXL Antibody against Triple-Negative Breast Cancer Patient-Derived Xenografts and Metastasis. Clin Cancer Res. 2017 Jun 1;23(11):2806-2816. doi
Daudigeos-Dubus E, Le Dret L, Bawa O, Opolon P, Vievard A, Villa I, Bosq J, Vassal G, Geoerger B. Dual inhibition using cabozantinib overcomes HGF/MET signaling mediated resistance to pan-VEGFR inhibition in orthotopic and metastatic neuroblastoma tumors. Int J Oncol. 2017 Jan;50(1):203-211. doi: 10.3892/ijo.2016.3792. Epub 2016 Dec 6. PubMed
Davra V, Kimani SG, Calianese D, Birge RB. Ligand Activation of TAM Family Receptors-Implications for Tumor Biology and Therapeutic Response. Cancers (Basel). 2016 Nov 29;8(12). pii
Wells MF, Salick MR, Wiskow O, Ho DJ, Worringer KA, Ihry RJ, Kommineni S, Bilican B, Klim JR, Hill EJ, Kane LT, Ye C, Kaykas A, Eggan K. Genetic Ablation of AXL Does Not Protect Human Neural Progenitor Cells and Cerebral Organoids from Zika Virus Infection. Cell Stem Cell. 2016 Dec 1;19(6):703-708. doi: 10.1016/j.stem.2016.11.011. PubMed
Retallack H, Di Lullo E, Arias C, Knopp KA, Laurie MT, Sandoval-Espinosa C, Mancia Leon WR, Krencik R, Ullian EM, Spatazza J, Pollen AA, Mandel-Brehm C, Nowakowski TJ, Kriegstein AR, DeRisi JL. Zika virus cell tropism in the developing human brain and inhibition by azithromycin. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14408-14413. Epub 2016 Nov 29. PubMed
Zhang L, Huang Y, Zhuo W, Zhu Y, Zhu B, Chen Z. Fisetin, a dietary phytochemical, overcomes Erlotinib-resistance of lung adenocarcinoma cells through inhibition of MAPK and AKT pathways. Am J Transl Res. 2016 Nov 15;8(11):4857-4868. eCollection 2016. PubMed
Ruiz-Morales JM, Heng DY. Cabozantinib in the treatment of advanced renal cell carcinoma
Cai YR, Dong YJ, Wu HB, Yu DP, Zhou LJ, Su D, Zhang L, Chen XJ. Expression level of CRKL and AXL combined with exon 19 deletion in EGFR and ALK status confer differential prognosis of lung adenocarcinoma subtypes. Oncol Lett. 2016 Nov;12(5):3312-3322. Epub 2016 Sep 2. PubMed
Miller MA, Sullivan RJ, Lauffenburger DA. Molecular Pathways
Kariolis MS, Miao YR, Diep A, Nash SE, Olcina MM, Jiang D, Jones DS 2nd, Kapur S, Mathews II, Koong AC, Rankin EB, Cochran JR, Giaccia AJ. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest. 2017 Jan 3;127(1):183-198. doi
Ma W, Li S, Ma S, Jia L, Zhang F, Zhang Y, Zhang J, Wong G, Zhang S, Lu X, Liu M, Yan J, Li W, Qin C, Han D, Qin C, Wang N, Li X, Gao GF. Zika Virus Causes Testis Damage and Leads to Male Infertility in Mice. Cell. 2016 Dec 1;167(6):1511-1524.e10. doi
Bergqvist M, Holgersson G, Bondarenko I, Grechanaya E, Maximovich A, Andor G, Klockare M, Thureson M, Jerling M, Harmenberg J. Phase II randomized study of the IGF-1R pathway modulator AXL1717 compared to docetaxel in patients with previously treated, locally advanced or metastatic non-small cell lung cancer. Acta Oncol. 2017 Mar;56(3):441-447. doi
Sholl LM, Do K, Shivdasani P, Cerami E, Dubuc AM, Kuo FC, Garcia EP, Jia Y, Davineni P, Abo RP, Pugh TJ, van Hummelen P, Thorner AR, Ducar M, Berger AH, Nishino M, Janeway KA, Church A, Harris M, Ritterhouse LL, Campbell JD, Rojas-Rudilla V, Ligon AH, Ramkissoon S, Cleary JM, Matulonis U, Oxnard GR, Chao R, Tassell V, Christensen J, Hahn WC, Kantoff PW, Kwiatkowski DJ, Johnson BE, Meyerson M, Garraway LA, Shapiro GI, Rollins BJ, Lindeman NI, MacConaill LE. Institutional implementation of clinical tumor profiling on an unselected cancer population. JCI Insight. 2016 Nov 17;1(19):e87062. doi: 10.1172/jci.insight.87062. PubMed
Sensi M, Canevari S, Tomassetti A. Axl in ovarian cancer
Batlle M, Campos B, Farrero M, Cardona M, Gonzlez B, Castel MA, Ortiz J, Roig E, Pulgarn MJ, Ramrez J, Bedini JL, Sabat M, de Frutos PG, Prez-Villa F. Data on clinical characteristics of a heart failure patients' cohort with reduced ejection fraction and analysis of the circulating values of five different heart failure biomarkers; high sensitivity troponin T, galectin-3, C-terminal propeptide of type I procollagen, soluble AXL and BNP. Data Brief. 2016 Nov 3;9:876-882. eCollection 2016 Dec. PubMed
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Correction
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