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参考文献: Arhgap15

Camilleri M, Sandler RS, Peery AF. Etiopathogenetic Mechanisms in Diverticular Disease of the Colon. Cell Mol Gastroenterol Hepatol. 2019 Jul 25. pii: S2352-345X(19)30095-5. doi
Liu ZD, Mou ZX, Che XH, Wang K, Li HX, Chen XY, Guo XM. ARHGAP15 regulates lung cancer cell proliferation and metastasis via the STAT3 pathway. Eur Rev Med Pharmacol Sci. 2019 Jul;23(13):5840-5850. doi
Pan S, Deng Y, Fu J, Zhang Y, Zhang Z, Ru X, Qin X. Decreased expression of ARHGAP15 promotes the development of colorectal cancer through PTEN/AKT/FOXO1 axis. Cell Death Dis. 2018 Jun 4;9(6):673. doi
Zamboni V, Armentano M, Berto G, Ciraolo E, Ghigo A, Garzotto D, Umbach A, DiCunto F, Parmigiani E, Boido M, Vercelli A, El-Assawy N, Mauro A, Priano L, Ponzoni L, Murru L, Passafaro M, Hirsch E, Merlo GR. Hyperactivity of Rac1-GTPase pathway impairs neuritogenesis of cortical neurons by altering actin dynamics. Sci Rep. 2018 May 8;8(1):7254. doi
Takagi K, Miki Y, Onodera Y, Ishida T, Watanabe M, Sasano H, Suzuki T. ARHGAP15 in Human Breast Carcinoma
Liao X, Huang K, Huang R, Liu X, Han C, Yu L, Yu T, Yang C, Wang X, Peng T. Genome-scale analysis to identify prognostic markers in patients with early-stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy. Onco Targets Ther. 2017 Sep 12;10:4493-4506. doi
Graziano BR, Gong D, Anderson KE, Pipathsouk A, Goldberg AR, Weiner OD. A module for Rac temporal signal integration revealed with optogenetics. J Cell Biol. 2017 Aug 7;216(8):2515-2531. doi
Sigurdsson S, Alexandersson KF, Sulem P, Feenstra B, Gudmundsdottir S, Halldorsson GH, Olafsson S, Sigurdsson A, Rafnar T, Thorgeirsson T, Srensen E, Nordholm-Carstensen A, Burcharth J, Andersen J, Jrgensen HS, Possfelt-Mller E, Ullum H, Thorleifsson G, Masson G, Thorsteinsdottir U, Melbye M, Gudbjartsson DF, Stefansson T, Jonsdottir I, Stefansson K. Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis. Nat Commun. 2017 Jun 6;8:15789. doi
Campa CC, Germena G, Ciraolo E, Copperi F, Sapienza A, Franco I, Ghigo A, Camporeale A, Di Savino A, Martini M, Perino A, Megens RT, Kurz AR, Scheiermann C, Sperandio M, Gamba A, Hirsch E. Rac signal adaptation controls neutrophil mobilization from the bone marrow. Sci Signal. 2016 Dec 20;9(459):ra124. doi: 10.1126/scisignal.aah5882. PubMed
Sun Z, Zhang B, Wang C, Fu T, Li L, Wu Q, Cai Y, Wang J. Forkhead box P3 regulates ARHGAP15 expression and affects migration of glioma cells through the Rac1 signaling pathway. Cancer Sci. 2017 Jan;108(1):61-72. doi: 10.1111/cas.13118. Epub 2017 Jan 23. PubMed
Zamboni V, Armentano M, Sar G, Ciraolo E, Ghigo A, Germena G, Umbach A, Valnegri P, Passafaro M, Carabelli V, Gavello D, Bianchi V, D'Adamo P, de Curtis I, El-Assawi N, Mauro A, Priano L, Ferri N, Hirsch E, Merlo GR. Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits. Sci Rep. 2016 Oct 7;6:34877. doi
lvarez I, Prez-Pardal L, Traor A, Fernndez I, Goyache F. African Cattle do not Carry Unique Mutations on the Exon 9 of the ARHGAP15 Gene. Anim Biotechnol. 2016;27(1):9-12. doi
Radu M, Rawat SJ, Beeser A, Iliuk A, Tao WA, Chernoff J. ArhGAP15, a Rac-specific GTPase-activating protein, plays a dual role in inhibiting small GTPase signaling. J Biol Chem. 2013 Jul 19;288(29):21117-25. doi: 10.1074/jbc.M113.459719. Epub 2013 Jun 11. PubMed
Xu J, Zhou X, Wang J, Li Z, Kong X, Qian J, Hu Y, Fang JY. RhoGAPs attenuate cell proliferation by direct interaction with p53 tetramerization domain. Cell Rep. 2013 May 30;3(5):1526-38. doi
Ullah I, Lee HY, Kim MJ, Shah SA, Badshah H, Kim TH, Chung HJ, Yang BC, Kim MO. Rho GTPase activating protein 15 (arhGAP15) siRNA effect apoptosis-induced by ethanol in bovine fibroblast cells. Pak J Pharm Sci. 2013 May;26(3):605-10. PubMed
Capitan A, Allais-Bonnet A, Pinton A, Marquant-Le Guienne B, Le Bourhis D, Grohs C, Bouet S, Clment L, Salas-Cortes L, Venot E, Chaffaux S, Weiss B, Delpeuch A, No G, Rossignol MN, Barbey S, Dozias D, Cobo E, Barasc H, Auguste A, Pannetier M, Deloche MC, Lhuilier E, Bouchez O, Esquerr D, Salin G, Klopp C, Donnadieu C, Chantry-Darmon C, Hayes H, Gallard Y, Ponsart C, Boichard D, Pailhoux E. A 3.7 Mb deletion encompassing ZEB2 causes a novel polled and multisystemic syndrome in the progeny of a somatic mosaic bull. PLoS One. 2012;7(11):e49084. doi
Mulatinho MV, de Carvalho Serao CL, Scalco F, Hardekopf D, Pekova S, Mrasek K, Liehr T, Weise A, Rao N, Llerena JC Jr. Severe intellectual disability, omphalocele, hypospadia and high blood pressure associated to a deletion at 2q22.1q22.3
Noyes H, Brass A, Obara I, Anderson S, Archibald AL, Bradley DG, Fisher P, Freeman A, Gibson J, Gicheru M, Hall L, Hanotte O, Hulme H, McKeever D, Murray C, Oh SJ, Tate C, Smith K, Tapio M, Wambugu J, Williams DJ, Agaba M, Kemp SJ. Genetic and expression analysis of cattle identifies candidate genes in pathways responding to Trypanosoma congolense infection. Proc Natl Acad Sci U S A. 2011 May 31;108(22):9304-9. doi
Costa C, Germena G, Martin-Conte EL, Molineris I, Bosco E, Marengo S, Azzolino O, Altruda F, Ranieri VM, Hirsch E. The RacGAP ArhGAP15 is a master negative regulator of neutrophil functions. Blood. 2011 Jul 28;118(4):1099-108. doi
Leikauf GD, Concel VJ, Liu P, Bein K, Berndt A, Ganguly K, Jang AS, Brant KA, Dietsch M, Pope-Varsalona H, Dopico RA Jr, Di YP, Li Q, Vuga LJ, Medvedovic M, Kaminski N, You M, Prows DR. Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1. Am J Respir Crit Care Med. 2011 Jun 1;183(11):1499-509. doi
Konstantinidou V, Covas MI, Muoz-Aguayo D, Khymenets O, de la Torre R, Saez G, Tormos Mdel C, Toledo E, Marti A, Ruiz-Gutirrez V, Ruiz Mendez MV, Fito M. In vivo nutrigenomic effects of virgin olive oil polyphenols within the frame of the Mediterranean diet
Smigiel R, Szafranska A, Czyzewska M, Rauch A, Zweier Ch, Patkowski D. Severe clinical course of Hirschsprung disease in a Mowat-Wilson syndrome patient. J Appl Genet. 2010;51(1):111-3. PubMed
Akagi K, Li J, Stephens RM, Volfovsky N, Symer DE. Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition. Genome Res. 2008 Jun;18(6):869-80. doi
Katoh Y, Katoh M. Identification and characterization of ARHGAP27 gene in silico. Int J Mol Med. 2004 Nov;14(5):943-7. PubMed
Katoh M, Katoh M. Characterization of human ARHGAP10 gene in silico. Int J Oncol. 2004 Oct;25(4):1201-6. PubMed
Seoh ML, Ng CH, Yong J, Lim L, Leung T. ArhGAP15, a novel human RacGAP protein with GTPase binding property. FEBS Lett. 2003 Mar 27;539(1-3):131-7. PubMed


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